Flights from John Wayne Airport - Santa Ana to Knoxville
Plane tickets John Wayne Airport - Santa Ana – Knoxville
Looking for affordable flights from John Wayne Airport - Santa Ana to Knoxville? Our site offers the best prices and a convenient search to plan your ideal trip. Book now and start your adventure without extra costs or hassle!
See also:
- Flights from Knoxville to John Wayne Airport - Santa Ana for the return trip
- Flights from John Wayne Airport - Santa Ana to any destination
- Fares from Knoxville to any destination
- Flights from United States to any destination
- Prices for flights to John Wayne Airport - Santa Ana
- Cheap tickets to United States
- Find flights from Los Angeles to United States
- Flights from Knoxville to United States
- Flights from United States to United States
- Cheap flights from Los Angeles to Knoxville
- Cheap flights from Knoxville to Los Angeles
Flight schedule John Wayne Airport - Santa Ana Knoxville 2026
Flights from John Wayne Airport - Santa Ana to United States
Below are the most popular routes from John Wayne Airport - Santa Ana to United States, sorted by the lowest available fares for different travel dates with no commission.
Frontier Airlines
F9 3738
14:46
John Wayne Airport - Santa Ana
14.12.2026
1h 15m
Direct flight
16:01
Las Vegas
14.12.2026
from $29
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Frontier Airlines
F9 4372
12:33
John Wayne Airport - Santa Ana
10.12.2026
2h 19m
Direct flight
15:52
Denver
10.12.2026
from $51
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Allegiant Air
G4 639
20:33
John Wayne Airport - Santa Ana
08.11.2026
1h 29m
Direct flight
23:02
Phoenix
08.11.2026
from $55
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Frontier Airlines
F9 3581
18:39
John Wayne Airport - Santa Ana
03.12.2026
1h 42m
Direct flight
20:21
San Francisco
03.12.2026
from $56
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Southwest Airlines
WN 4255
09:30
John Wayne Airport - Santa Ana
08.12.2026
1h 20m
Direct flight
10:50
Oakland
08.12.2026
from $89
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Flights from other airports to Knoxville
The cheapest flights from other airports to Knoxville with no commission.
American Airlines
AA 5294
20:55
O'Hare International Airport
01.11.2026
1h 52m
Direct flight
23:47
Knoxville
01.11.2026
from $105
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Southwest Airlines
WN 485
11:00
Dallas Love Field
15.12.2026
2h 5m
Direct flight
14:05
Knoxville
15.12.2026
from $131
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Etihad Airways
EY 844
23:50
Sheremetyevo International Airport
01.11.2026
45h 52m
with 2 stops
13:42
Knoxville
03.11.2026
from $1,196
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Frequently asked questions about the route John Wayne Airport - Santa Ana – Knoxville
How much does a flight from John Wayne Airport - Santa Ana to Knoxville cost?
Flight prices from John Wayne Airport - Santa Ana to Knoxville vary by season, day of week, and booking time. For current fares and the best deals, use our search tool to see all options and prices. The lowest fare is $197.
Which airlines fly from John Wayne Airport - Santa Ana to Knoxville?
The following airlines operate the route John Wayne Airport - Santa Ana — Knoxville: Southwest Airlines, United Airlines, American Airlines, Delta, Alaska Airlines, Emirates.
How long is the flight from John Wayne Airport - Santa Ana to Knoxville?
In the offers we recently observed from John Wayne Airport - Santa Ana to Knoxville, the fastest itinerary with at least one plane change took 7 hours and 23 minutes.
Is there a direct flight John Wayne Airport - Santa Ana — Knoxville?
The schedule data currently available to us does not show a nonstop flight from John Wayne Airport - Santa Ana to Knoxville. Other routings may be available — use our search to check options for your dates.
